A prototype of three-phase 12/10-pole SIPM machine is used for exemplification. Both the predicted and measured results are given to illustrate the proposed machine. c 2009 American Institute of Physics. [DOI: 10.1063/1.3067486]“
“In this work, we design and fabricate a miniaturized spiral-shaped microchannel device which can be used for mTOR inhibitor high-throughput particle/cell ordering, enrichment, and purification. To probe into the flow rate regulation mechanism, an experimental investigation is carried out on the focusing behaviors of particles with significantly different sizes in this

device. A complete picture of the focusing position shifting process is unfolded to clarify the confusing results obtained from flow regimes with different dominant forces in past research. Specifically, with the increase of the flow rate, particles are observed to first move towards the inner wall under the dominant inertial migration, then stabilize at a specific position and finally shift away from the inner wall due to the alternation of the dominant force. Novel phenomena of focusing instability, co-focusing, and focusing position interchange

of differently sized particles are also observed and investigated. Based on the obtained experimental data, we develop and validate, Autophagy inhibitor ic50 for the first time, a five-stage model of the particle focusing process with increasing flow rate for interpreting particle behaviors in terms of the competition between inertial lift and Dean drag forces. These new experimental findings and the proposed process model provide an important supplement to the existing mechanism of inertial particle flow and enable more flexible and precise particle manipulation. Additionally, we examine the focusing behaviors of bioparticles with a polydisperse size distribution p53 inhibitor to validate the explored mechanisms and thus help realize efficient enrichment and purification of these particles. (C) 2013 AIP Publishing LLC.”
“Entanglement of the umbilical cord with fetal body parts is known to occur in early pregnancy. This

can potentially compromise the cord blood flow and cause fetal demise. We report 3 instances of intrauterine fetal deaths in the 2nd trimester of pregnancy with longstanding cord entanglement. The cord had left impressions of entanglement on the entrapped growing fetal part. Restricted movements of the fetus due to cord entanglement led to reduced spiraling of the umbilical cord. Our case series demonstrates that tight entanglement of fetal body parts by the umbilical cord can cause fetal demise in the 2nd trimester. This event is associated with a straight umbilical cord. Thus, the presence of reduced spiraling in intrauterine fetal demise warrants a search for possible cord entanglement along with established causes, such as chromosomal and congenital anomalies.