Finally, factors linked to the programme represent the aspects of the implemented programme. These five broad categories of factors will be used to guide us in the identification of characteristics that can potentially contribute to the impact. The integration Wortmannin mTOR of CM services into each LSN will be examined according to the integrated care model recently suggested in England.26 This model proposes six essential dimensions of services integration based on patient experience: (1) consideration of patient and family needs; (2) communication with the patient and between practitioners; (3) access to information; (4) involvement in decision-making;

(5) care planning; and (6) transitions between various health professionals and practitioners. Research design This longitudinal research relies on a multiple embedded case study27 design based on a developmental evaluation approach (figure

1).28 29 Multiple case study is preferred as this design is well adapted to respond to a research question focused on the ‘how’ in a complex system (LSN), and in dynamic and varied contexts at the time of the study.27 30 We will work with four cases, the ‘case’ being the CM programme for high users of hospital services of each HSSC. The number of cases, fixed at four, appears optimal to obtain good diversity of contexts while ensuring the feasibility of the proposed approach. The four HSSCs selected are the first four in the region to have implemented CM in their organisation. Three different units of analysis will be interwoven to obtain an in depth understanding of each case, that is: (1) HSSC and LSN (‘macro’ level); (2) CM programme for high users of services (‘meso’ level) and (3) patients who are high users of services (‘micro’ level). In addition to allowing for an in depth analysis of each case, the multiple case study design will offer analysis strategies to systematically compare trends observed between cases. Figure 1 Research

design and project outline. CM, case management; GSK-3 HSSC, health and social services centre; QUAL, qualitative data; QUAN, quantitative data. The team proposes to use a developmental evaluation approach in response to decision-makers’ needs for ongoing access to information required to inform and orient their decisions. Developmental evaluation that builds on an efficient partnership between researchers and decision-makers helps support adaptive learning in emerging and complex initiatives.31 It consists of collaboratively asking evaluative questions and collecting data allowing for feedback, and to support decision-making and modifications to be made to improve the programme.32 Considered as a rigorous evaluative approach, it allows for the required flexibility in a context of evolving programmes in real clinical settings.