Moreover, if there is a decreased fetal movement, one

fetal health diagnostic test such as sonography, non-stress test, or biophysical profile should be used, and if needed, interventional procedures should be performed.
Dear Editor, We would like to thank Dr Badrodin Najmi for his comments on our paper published in a recent issue of IJMS.1 The followings are our response to the points raised by Dr. Najmi. As it was explained in the result section of the abstract, 44% of interviewees had spousal relationship with their patients. The rest of the participants, who were from minor groups, Inhibitors,research,lifescience,medical were presented in detail in the text of the paper. In the Materials and Methods section, it was clearly explained that the each interviewee was invited and interviewed separately. Moreover, as it was indicated in the paper, the study was an interventional one. Also, lines 1-7 of the second MDV3100 paragraph of Materials and Inhibitors,research,lifescience,medical Methods section read that the interviewees were introduced by HIV positive patients and were included Inhibitors,research,lifescience,medical in the study only if

they knew about the positivity of HIV status of their patients, and had close and trusty relationships with them. Children couldn’t be subjects for this study. The Materials and Methods section described in details that every Carfilzomib mechanism participant took part in the study twice at two separate counseling sessions. The theoretical basis of intervention was mentioned in lines 9-16 of the second paragraph of the introduction. Also, the guidelines for counseling were mentioned in lines 25-28 of the second paragraph of this section. In regards to the establishment of the face or content validity of the questionnaire, it is believed that the use of expert opinion is among the most popular methods Inhibitors,research,lifescience,medical to validate a questionnaire, Inhibitors,research,lifescience,medical which covers a highly specialized issue such as AIDS related subjects.1-3 Indeed, there is

not a gold statistical method to define the content validity co-efficiency,4 although factor analysis may only help this assessment.5 The face validity and content validity in some areas are mainly based on expert opinion and not statistics.4 However, experts’ opinion about the content validity of an issue may not either be definite, or the same.4,6 We used Kuder-Richarson AV-951 method (KR20) for the estimation of reliability, because the questionnaire items were binary and such as method was appropriate for the evaluation of internal consistency.5 The reliabilities of the knowledge and behavior sections of the questionnaire were 0.727 and 0.896, respectively. All items of table 2 in the paper include attitude aspects of HIV patients’ families toward their patients. Items 1, 3, 5 and 6 relate directly to the patients and items 2 and 4 relate indirectly to them by means of intermediates. Table 2 includes binary questions that couldn’t be scored using Linkert Scale.