Prolonged endotracheal intubation had been discovered is a danger element for pulmonary aspiration after the extubation. In this research, we now have tried to evaluate the prevalence of airway penetration and aspiration among mechanically ventilated patient just who got technical air flow for a time period of 48 hours or even more. This cross-sectional research was done among non-neurologic critically ill customers who’d an endotracheal tube for longer than 48 hours and who got extubated consequently. Such patients were taken for a fiberoptic endoscopic swallow study following the initial evaluation by a speech pathologist. Airway penetration and aspiration was evaluated by an eight-point penetration-aspiration scale after giving a test feed. Information of 99 patients were examined. Mean extent of intubation had been 5.9 days. 1% for the patients had aspiration and 20% of the customers had differing degrees of penetration. Duration of endotracheal intubation, age, intercourse, comorbidities, admission diagnosis, and size of the endotracheal tube were n Scale Using versatile Endoscopy A Cross-sectional Study. Indian J Crit Care Med 2023;27(9)651-654. Stroke is a respected reason behind morbidity and death all over the world. Developing countries, however, nevertheless lag behind in supplying timely thrombolytic treatment (TLT) to many qualified clients due to numerous explanations https://www.selleck.co.jp/products/selonsertib-gs-4997.html . This research aims to determine such facets. This was a descriptive observational research done during a period of 1 . 5 years at a tertiary care teaching hospital and included 252 intense ischemic stroke patients of which 200 are not thrombolyzed. The reason why for nonthrombolysis had been taped and examined. The study included 252 acute ischemic swing patients of which just 20% were thrombolyzed. Associated with 200 nonthrombolyzed clients, 55% appeared out from the window duration while patient-related facets were the next biggest element preventing thrombolysis. Hospital facets at 14% and monetary constraints at 4.5per cent added substantially. Delayed consent appeared as a significant factor making 6% of this delays. Stroke thrombolysis still deals with numerous pre- and intrahospital obstacles in Asia. There clearly was an immediate need certainly to enhance infrastructure and business streamlining to allow qualified customers to receive prompt therapy. Shah A, Diwan A. Stumbling Blocks to Stroke Thrombolysis An Indian Attitude. Indian J Crit Care Med 2023;27(9)616-619.Shah A, Diwan A. Stumbling Blocks to Stroke Thrombolysis An Indian Attitude. Indian J Crit Care Med 2023;27(9)616-619. . There clearly was simple data regarding the medical anthropology regional mechanisms of opposition. Given the current healing difficulties, it is vital to know the neighborhood enzymatic patterns and antibiograms. The opposition prices for amikacin, tigecycline, minocycline, and fluoroquinolones were 88, 82, 50, and 88% correspondingly. OXA-23 was the absolute most commonly isolated enzyme (86% associated with the isolates produced OXA-23) accompanied by OXA-51 and NDM. The overall death ended up being high (58%). On univariate analysis, pneumonia, and greater Pitt’s bacteremia score were significantly involving death ( = 0.001 correspondingly). Of ality among customers with Carbapenem Resistant Acinetobacter Baumannii (CRAB) Bacteremia real life Research from a Tertiary Center in India. Indian J Crit Care Med 2023;27(9)663-668. Refractory shock, which does not respond to traditional vasopressor treatment, is a common complication of sepsis. Methylene blue has emerged as a potential adjunctive treatment choice for reversing refractory shock in sepsis. The purpose of this research was to evaluate the influence of intravenous methylene blue infusion on hemodynamic improvement and death in patients with refractory surprise. This is an observational prospective study for the duration of six months performed at intensive treatment a health college and teaching hospital including 76 patients with an analysis of septic surprise requiring vasopressor treatment. Intravenous (IV) methylene blue ended up being infused as a bolus dose with 2 mg/kg dose in 20 minutes and its own reaction to imply arterial blood circulation pressure, decline in shoulder pathology vasopressor treatment, lactate level, and urine output ended up being taped in next 2 hours. Clients with enhancement in mean arterial stress (MAP) by 10% or decrease in vasopressor therapy within the next 2 hours had been leveled as responder. The length of int (21.97 vs 15.93 days, The usage IV methylene blue in refractory shock as an adjuvant treatment considerably enhanced the mean arterial blood circulation pressure and reduced the requirement of vasopressor treatment as well as improvement into the success time. But, there was no change in the death, duration of ICU stay, ventilator-free days, or occurrence of AKI into the clients. Rajbanshi LK, Bajracharya A, Arjyal B, Devkota D. may use of Intravenous Methylene Blue enhance the Hemodynamics and upshot of the Patients with Refractory Septic Shock? An Observational Learn. Indian J Crit Care Med 2023;27(9)669-674.Rajbanshi LK, Bajracharya A, Arjyal B, Devkota D. may use of Intravenous Methylene Blue Improve the Hemodynamics and Outcome of the people with Refractory Septic Shock? An Observational Learn. Indian J Crit Care Med 2023;27(9)669-674. Sepsis is involving broad variable coagulation abnormalities. Thromboelastography (TEG) effortlessly steps the viscoelastic properties of the clots. This study aims to illustrate the viscoelastic properties of clot high quality and mass in sepsis and septic shock patients utilizing TEG, as a very good device over standard coagulation tests. A single-center, potential observational study had been performed.