Recent reports about leishmaniasis show a few number of drugs available, indicating the

necessity of new drugs. In this study, the ethanol extract and fractions of Pityrogramma calomelanos (L.) link. (Pteridaceae) were assayed to verify the cytotoxicity and invitro leishmanicidal activity against promastigote forms of Leishmania brasiliensis. The cytotoxic assay was performed using fibroblasts NCTC929. The studies indicated a leishmanicidal effect of the ethanol extract and the ethyl-acetate fraction. However, a high cytotoxic effect was observed. The hexane and methanol fractions did not show leishmanicidal activity, nor cytotoxic effect. The phytochemical screening detected the presence of alkaloids, a class of secondary metabolites with a known leishmanicidal activity. This is the

first study reporting an anti-Leishmania and cytotoxic https://www.selleckchem.com/products/ly2157299.html effect of P. calomelanos, being an interesting approach in the search for drugs against this disease.”
“The objective of this study was to evaluate the antimicrobial and antioxidative effects of the onion peels extract prepared via the subcritical water extraction (SWE) method. First, the number of cells treated with the extract was reduced by 0.7-1.1 log CFU/mL compared with the control. The SWE extract showed 76.08% scavenging activity and it was more effective than butylated hydroxytoluene selleckchem (BHT) at 61.3 ppm in lipid peroxidation inhibitory effects. In addition, the antioxidative effect of SWE extract measured via the ferric thiocyanate (FTC) method was 2-fold that of BHT. The results of this

study suggest that the onion peels extract prepared via the SWE method may have potential alternative antimicrobial and antioxidative effects as functional substances.”
“A simple and practical scheme for a directional bending sensor based on a sampled chirped fiber Bragg grating is proposed. The proposed sensing method has temperature insensitivity. The wavelength spacing in the reflection spectrum of a sampled chirped fiber Bragg grating is changed by bending because of the modification of the chirp ratio. As positive or negative bending is applied to the sampled chirped fiber Bragg grating embedded on a flexible PD0325901 cantilever beam, the wavelength spacing increases or decreases because of the induction of the tension and the compression strain gradient along the fiber grating. However, the wavelength spacing is not changed by the applied temperature. Since the effect of the temperature variation along the grating length remains the same, the chirp ratio is independent of the applied temperature change. Regardless of temperature change, it is therefore possible to measure the direction and the variation of bending.”
“The essential oils from the leaves of Annona pickelii and Annona salzmannii (Annonaceae) were obtained by hydrodistillation using a Clevenger apparatus, and analysed by GC-MS and GC-FID.