Results: Overall, the change in lipids was relatively small [<= 5% except for Lp(a), which was 20-25%], and there was no significant difference in the mean change of any lipid variable between the active and placebo groups.

Conclusions: Our results indicate that CaD supplementation is not associated with lipid changes over 5 y. Existing and future CaD trials should

consider evaluating this association for different doses of supplements. This study was registered Selleck DAPT at clinicaltrials.gov as NCT00000611. Am J Clin Nutr 2010; 91: 894-9.”
“Background and Aim: The aim of the present work was to evaluate the relationship between energy-generating nutrients and the presence of central and overall obesity after correcting for socio-demographic, lifestyle and clinical characteristics, among healthy elders. Methods and Results: During 2005e2007, 553 elderly men and 637 elderly women (mean age 74 +/- 7 years) from eight Mediterranean islands in Greece and Cyprus, were enrolled. The retrieved information included demographic, bio-clinical and dietary characteristics. MedDiet-Score assessed adherence CHIR-99021 PI3K/Akt/mTOR inhibitor to the Mediterranean dietary pattern.

The prevalence of obesity was 27% in males and 39% in females (p < 0.001), while 73% of males and 87% of females had central

obesity. The prevalence of diabetes, hypercholesterolemia and hypertension was higher in the obese than in the non-obese participants (p < 0.01). After adjusting for various confounders, a 1% increase in carbohydrate consumption was associated with a 12% (95% CI 0.78-0.99) lower likelihood of having central obesity, while a 1% increase in carbohydrate

and protein consumption was associated with a 14% (95% CI 0.78-0.95) and 16% (95% CI 0.72-0.97) lower likelihood of being obese, respectively. Vegetable protein was found to be associated Adriamycin in vitro with a 15% (95% CI 0.77-0.93) lower likelihood of being obese while, only low glycemic index carbohydrates seem to be associated with a 6% (95% CI 0.90-0.98) lower likelihood of having central obesity.

Conclusions: The presented findings suggest that a diet high in carbohydrates and vegetable protein is associated with a lower likelihood of being obese and may help elderly people to preserve normal weight. (C) 2009 Elsevier B.V. All rights reserved.”
“With Fe compensation, the heavy rare earth element Gd-filled Gd(y)Fe(x)Co(4-x)Sb(12) (x < 2) skutterudites have been successfully synthesized by melting-annealing approach. Fe substitution on the Co site brings two contrary effects on Gd filling: charge compensation which enhances the filling fraction of Gd, and Lattice expansion which is deleterious for the stability of filled compounds that contain smaller atoms. When Fe content is less than 1.7, pure Gd(y)Fe(x)Co(4-x)Sb(12) compounds are obtained and the Gd maximum filling fraction (y(max)) increases with Fe content. The power factor (S(2)sigma) of the Gd(y)Fe(x)Co(4-x)Sb(12) increases with Fe content.