Serious adverse effects were 6 (8%) severe infections requiring hospital admission, 2 (3%) developed malignancy (1 skin SCC, 1 prostate
cancer), 27 (36%) were hospitalized during treatment and one patient died of pneumonia. Conclusions: In this real-life cohort of IBD patients managed in a regional setting, although most would not have been eligible Selleckchem PD-332991 for enrolment in a pivotal RCT of biologic agents, long-term treatment with IFX or ADA was safe and effective in the majority of patients. KE NAPTHALI, R FOSTER John Hunter Hospital, Newcastle, University of Newcastle Introduction: Tuberculosis (TB) is an uncommon disease in Australia, particularly in the large population of Australian-born/Non-indigenous (ABNI) population. Cases are reported at increased rates amongst the indigenous population and in the population of immigrants from endemic regions. In the ABNI population, the incidence remains very low with a rate of 0.9 per 100,0001. The total number of cases reported for all population groups in 2009 was 13221 and of the total number of cases only 2 percent1 of all cases were defined as military TB. We present a case of military TB in a 27 year old Caucasian woman with minimal or no risk factors and very marginal overseas travel risk who presented with diarrhoea and symptoms of colitis to a tertiary referral hospital in the Hunter region in late 2013. She proceeded
to colonoscopy which macroscopically showed Colitis most consistent JQ1 mouse with Crohns disease and was commenced on immunossupression.
She subsequently came unwell with fevers and medchemexpress sweats and was found ultimately to have Miliary tuberculosis, after having been on immunosuppressive therapy including a thiopurine for 6 weeks. This case demonstrates a rare example of GI tuberculosis masquerading as colitis in a vanishingly low risk population group. Case Discussion: A 27 year old Australian born Caucasian woman presented to the emergency department of a tertiary referral hospital in late December 2013 complaining of a three week history of crampy periumbilical pain. She had intermittent diarrhoea without mucous, bleeding or melena. Her GP had recently diagnosed iron deficiency anemia and had commenced oral iron supplementation with expectant referral to a Gastroenterologist for esophagogastroduodenoscopy (OGD). The only other presenting complaint was unintentional weight loss over the preceding 2 weeks and a new cough for the last 6 months. She reported no fevers or rigors in the previous 6 months. The patient’s past medical history was unremarkable. Her medications included the oral contraceptive pill and recently had started esomeprazole and Fe supplements. She was a fit and well Caucasian woman of average build without any surgical or obstetric history. She had not been institutionalized and her only overseas travel was to Fiji on holiday.