Table 1 Basic characteristics of study subjects (N = 584) Variable     Mean (SD) Age (years)  64.4 (9.6) Height (cm)  149.7 (6.1) Weight (kg)  52.4 (8.9) Body mass index (kg/m2) LBH589 manufacturer  23.4 (3.5)   Number (%) Women with at least one vertebral deformity  86 (14.7 %) Women with vertebral osteoarthritis  431 (73.8 %) Women with at least one painful joint at nonspine site  283/575 (49.2 %)a Postmenopausal  530 (90.8 %) aData is missing for some individuals, but Selleck Vistusertib denominator is given

Table 2 The prevalence of women with back pain in the previous 1 month according to age Age group (years) No. of subjects Upper back pain (no. (%)) Low back pain (no. (%)) Upper or low back pain

(no. (%)) 40–49 45 6 (13.3) 7 (15.6) 11 (24.4) 50–59 123 23 (18.7) 27 (22.0) 40 (32.5) 60–69 217 36 (16.6) 39 (18.0) 58 (26.7) 70–79 169 39 (23.1) 32 (18.9) 56 (33.1) 80–89 30 8 (26.7) 8 (26.7) 11 (36.7) Total 584 112 (19.2) 113 (19.4) 176 (30.1)     P = 0.08a P = 0.68a P = 0.32a aCochran–Armitage trend test Table 3 presents the frequency distribution of the three types of deformity and back pain. The majority of deformities CYT387 research buy were wedge, followed by endplate and crush. of deformities Location Pain     Thoracic Upper back Wedge 0 566 (96.9) 109/566 (19.3)   1 18 (3.1) 3/18 (16.7)   2+ 0 (0.0) –       P = 0.78a Endplate 0 574 (98.3) 109/574 (19.0)   1 8 (1.4) 3/8 (37.5)   2+ 2 (0.3) 0/2 (0.0)       P = 0.33a Crush 0 574 (98.3) 110/574 (19.2)   1 5 (0.9) 0/5 (0.0)   2+ 5 (0.9) 2/5 (40.0)       P = 0.27a Any 0 549 (94.0) 104/549 (18.9)   1 26 (4.5) 6/26 (23.1)   2+ 9 (1.5) 2/9 (22.2)       P = 0.85a     Lumbar

Low back Wedge 0 557 (95.4) 99/557 (17.8)   1 21 (3.6) 9/21 (42.9)   2+ 6 (1.0) 5/6 (83.3)       P < 0.0001a Endplate 0 561 (96.1) 103/561 (18.4)   1 16 (2.7) 4/16 (25.0)   2+ 7 (1.2) 6/7 (85.7)       P < 0.0001a Crush 0 574 (98.3) 109/574 Sitaxentan (19.0)   1 7 (1.2) 2/7 (28.6)   2+ 3 (0.5) 2/3 (66.7)       P = 0.094a Any 0 534 (91.4) 92/534 (17.2)   1 32 (5.5) 8/32 (25.0)   2+ 18 (3.1) 13/18 (72.2)       P < 0.0001a     Total Upper or low back Wedge 0 524 (89.7) 145/524 (27.7)   1 43 (7.4) 20/43 (46.5)   2+ 17 (2.9) 11/17 (64.7)       P = 0.0002a Endplate 0 543 (93.0) 156/543 (28.7)   1 23 (3.9) 9/23 (39.1)   2+ 18 (3.1) 11/18 (61.1)       P = 0.0082a Crush 0 562 (96.2) 167/562 (29.7)   1 13 (2.2) 5/13 (38.5)   2+ 9 (1.5) 4/9 (44.4)       P = 0.51a Any 0 498 (85.3) 136/498 (27.3)   1 44 (7.5) 18/44 (40.9)   2+ 42 (7.2) 22/42 (52.4)       P = 0.