Ten healthy adult volunteers (mean age +/- standard deviation, 25 years +/- 4; seven men, three women) underwent navigator-gated
three-dimensional MR angiography of the RCA at 7 T and 3 T. For 7 T, a custom-built quadrature radiofrequency transmit-receive surface coil was used. At 3 T, a commercial body radiofrequency transmit coil and a cardiac coil array for signal reception were used. Segmented k-space gradient-echo imaging with spectrally selective adiabatic fat suppression was performed, and imaging parameters were similar at both field strengths. Contrast-to-noise ratio between blood and epicardial https://www.selleckchem.com/products/smoothened-agonist-sag-hcl.html fat; signal-to-noise ratio of the blood pool; RCA vessel sharpness, diameter, and length; and navigator efficiency were quantified at both field strengths and compared by using a Mann-Whitney U test.
Results: The contrast-to-noise ratio between blood and epicardial fat was significantly improved at 7 T when compared with that at 3 T (87 +/- 34 versus 52 +/- 13; P = .01). Signal-to-noise ratio of the blood pool was increased at 7 T (109 6 47 versus 67 +/- 19; P = .02). Vessel sharpness obtained at 7 T was also higher (58% +/- 9 versus BVD-523 price 50% +/- 5; P = .04). At the same time,
RCA vessel diameter and length and navigator efficiency showed no significant field strength-dependent difference.
Conclusion: In our quantitative and qualitative study comparing in vivo human imaging of the RCA at 7 T and 3 T in young healthy volunteers, Bromosporine concentration parameters related to image
quality attained at 7 T equal or surpass those from 3 T. (C) RSNA, 2010″
“Relaxed epitaxial 100(pc) and 111(pc) oriented films (350 nm) of Pb(Zr(1-x)Ti(x))O(3) (0.2 <= x <= 0.4) on SrRuO(3)/SrTiO(3) substrates were grown by pulsed laser deposition and studied using high resolution synchrotron X-ray diffraction and transmission electron microscopy. The dielectric behavior and ferroelectric phase transition temperatures of the films were consistent with bulk PZT. However, weak 1/2311(pc) reflections in x-ray diffraction profiles were recorded above bulk T(Tilt) (as indicated in the Jaffe, Cooke, and Jaffe phase diagram, where pc denotes pseudocubic indices). Moreover, anomalies in the dielectric and ferroelectric response were detected above TTilt which are explained by coupling of short coherence or weakly tilted regions to the ferroelectric polarization. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3580328]“
“Background: Aberrant expression of microRNAs (miRNAs) has been implicated in oncogenesis of various tumors and primary cutaneous T cell lymphomas. Dicer, a ribonuclease III-like enzyme is essential for miRNA processing.
Objective: We initiated a retrospective study to characterize the alterations in the expression profile of Dicer in patients with primary cutaneous T cell lymphomas (CTCL).