“
“The main objective of this contribution is to point out the potentialities of cerium doped LuAG single crystal as pixels and fibers. We first show that after optimization of growth conditions using Bridgman technology, this composition exhibits very good performances for scintillating applications (up to 26 000 photons/MeV). When grown with the micropulling down technology, fiber shapes can be obtained while the intrinsic performances are preserved. For the future high energy experiments

requiring new detector concepts capable of delivering much richer informations about x- or gamma-ray energy deposition, unusual fiber shaped dense materials need to be developed. We demonstrate in this frame that cerium doped LuAG is a serious candidate for the next generation of ionizing NSC23766 purchase radiation calorimeters. (C) 2010 American Institute

check details of Physics. [doi: 10.1063/1.3452358]“
“Background: Technological advances during the last few decades have improved the success rate of surgery for the treatment of malignant spinal tumors. Nonetheless, many patients present with widespread tumor burden and minimal life expectancy, which excludes them from being surgical candidates. For these patients, palliative management is recommended.

Methods: The authors reviewed prospective and retrospective clinical studies as well as case series regarding palliative treatments for primary and metastatic spinal tumors.

Results: Analgesics, ranging from nonopioids to strong opioids, may be used depending on the degree of pain. Steroids may also improve pain relief, although they are associated

with a number of adverse events. Vertebroplasty and kyphoplasty are conservative treatments with high rates of pain relief and vertebral body stabilization. Radiotherapy is the gold standard for palliative management, with approximately 60% of patients experiencing a decrease in tumor-related spinal Selleckchem LY411575 pain and up to 35% experiencing complete relief. Stereotactic radiosurgery delivers high doses of radiation to patients to provide pain relief while also sparing delicate anatomical structures.

Conclusion: Palliative management of spinal tumors is diverse. Analgesics may be used in conjunction with radiotherapy and/or kyphoplasty or vertebroplasty to offer pain relief.”
“Aim:

The issue of medication safety is highly significant when anti-cancer therapy is used due to the high potential for harm from these agents and the disease context in which they are being used. This article reports on the development of multidisciplinary consensus guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy undertaken by a working group of the Clinical Oncological Society of Australia (COSA).