This study examined the frequency of acute stroke and the factors

This study examined the frequency of acute stroke and the factors associated with complications of stroke in India. In this prospective multicenter study, running from March 2008 to September 2009, 6 hospitals collected information on complications of first-ever stroke during admission. Complications were defined in accordance with standard criteria. Outcome at 30 days poststroke was assessed using the modified Rankin Scale. Stroke characteristics, length of hospital stay, and stroke severity (based on the National Institutes of Health Stroke Scale) were documented. Hematologic (ie, hemoglobin)

and biochemical (ie, total proteins and albumin) parameters also were obtained. A total of 449 patients out of the recruited 476 completed follow-up. The mean age was 58.1 +/-

13.7 years (range, 16-96 years), and the majority were men (n=282; 62.8%). The mean National Institutes of Stroke Scale score was 10.2 +/- 5.3. Overall, 206 patients (45.9%) experienced complications during admission. In the logistic regression analysis, limb weakness (odds ratio [OR], 0.12; CA3 research buy 95% confidence interval [CI], 0.02-0.67; P=.01), anemia (OR, 0.35; 95% CI, 0.15-0.81; P=.01), length of hospital stay (OR, 0.89; 95% CI, 0.85-0.94; P<.0001), and stroke severity (OR, 0.27; 95% CI, 0.10-0.72; P=.01) were the variables associated with complications. Such complications as urinary tract infection (OR, 0.31; 95% CI, 0.13-0.78; P=.01), chest infection (OR, 1.81; 95% CI, 1.12-2.93; P=.02), bedsores (OR, 3.52; 95% CI, 1.02-12.08; P=.05), other pain (OR, 0.21; 95% CI, 0.09-0.49; P<.0001), and depression (OR, 2.22; 95% CI, 1.30-3.80; P<.01) were associated with poor outcome. Our

study shows high rates of complication in acute stroke. Limb weakness, stroke severity, length of hospital stay, and anemia were the factors associated with complications. Other complications, such as urinary tract infection, chest infection, bedsores, other pain, and depression, can lead to poor outcome.”
“The learn more aim of the present study was to assess whether elevated B-type natriuretic peptide (BNP) levels, as an objective marker of heart failure, is a predictor of subsequent thromboembolic events in patients with atrial fibrillation (AF) during oral anticoagulant therapy. This was a post hoc analysis of a single-center, prospective, observational study. Consecutive patients with AF (261 patients, 74 +/- 9 years old, 153 paroxysmal AF) treated with warfarin were included for the analysis. BNP level at baseline examination was measured to assess the relationship of this parameter with subsequent thromboembolic events. BNP levels at the time of entry were 161 +/- 188 (5-1,500, median 105) pg/ml. During an average follow-up time of 762 +/- 220 (median 742) days, nine (1.8%/year) thromboembolic events occurred.

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