PubMedCrossRef 48. Moscoso M, del Solar G, Espinosa M: In vitro recognition of the replication origin of pLS1 and of plasmids of the pLS1 family by the RepB initiator protein. J Bacteriol 1995,177(24):7041–7049.PubMed 49. Priebe SD, Lacks SA: Region of the streptococcal plasmid pMV158 required for conjugative mobilization. J Bacteriol 1989,171(9):4778–4784.PubMed 50. Francia MV, Varsaki A, Garcillan-Barcia MP, Latorre A, Drainas C, de la Cruz F: A classification selleck kinase inhibitor scheme for mobilization regions of bacterial PRN1371 plasmids. FEMS Microbiol Rev

2004,28(1):79–100.PubMedCrossRef 51. Garcillan-Barcia MP, Francia MV, de la Cruz F: The diversity of conjugative relaxases and its application in plasmid classification. FEMS Microbiol Rev 2009,33(3):657–687.PubMedCrossRef 52. del Solar G, Giraldo

R, Ruiz-Echevarria MJ, Espinosa M, Diaz-Orejas R: Replication and control of circular bacterial plasmids. Microbiol Mol Biol Rev 1998,62(2):434–464.PubMed 53. DaMassa AJD, Tully JG, Rose DL, Pitcher D, Leach RH, Cottew GS: Mycoplasma auris sp. nov., Mycoplasma cottewii sp. nov., and Mycoplasma yeatsii sp. nov., new sterol-requiring mollicutes from the external ear canals of goats. Int J Syst Bacteriol 1994,44(3):479–484.PubMedCrossRef 54. Jimena ON, Laura JM, Elena MM, Alonso NH, Teresa QM: Association Selleck GSK126 of Raillietia caprae with the presence of Mycoplasmas in the external ear canal of goats. Prev Vet Med 2009,92(1–2):150–153.PubMedCrossRef 55. Lartigue C, Blanchard A, Renaudin J, Thiaucourt F, Sirand-Pugnet P: Host specificity of mollicutes oriC plasmids: functional analysis of replication origin. Nucleic Acids Res 2003,31(22):6610–6618.PubMedCrossRef MTMR9 56. Saitou N, Nei M: The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 1987,4(4):406–425.PubMed 57. Felsenstein J: Phylogenies from molecular sequences: inference and reliability.

Annu Rev Genet 1988, 22:521–565.PubMedCrossRef 58. Sirand-Pugnet P, Lartigue C, Marenda M, Jacob D, Barré A, Barbe V, Schenowitz C, Mangenot S, Couloux A, Segurens B, et al.: Being pathogenic, plastic, and sexual while living with a nearly minimal bacterial genome. PLoS Genet 2007,3(5):e75.PubMedCrossRef 59. Davies J, Smith DI: Plasmid-determined resistance to antimicrobial agents. Annu Rev Microbiol 1978, 32:469–518.PubMedCrossRef 60. Valdes AM, Pinero D: Phylogenetic estimation of plasmid exchange in bacteria. Evolution 1992,46(3):641–656.CrossRef 61. Smillie C, Garcillan-Barcia MP, Francia MV, Rocha EP, de la Cruz F: Mobility of plasmids. Microbiol Mol Biol Rev 2010,74(3):434–452.PubMedCrossRef 62. de Antonio C, Farias ME, de Lacoba MG, Espinosa M: Features of the plasmid pMV158-encoded MobM, a protein involved in its mobilization. J Mol Biol 2004,335(3):733–743.PubMedCrossRef Competing interests All the authors declare no competing interests. Authors’ contributions MB, FT, VM and ED-F carried out most of the experiments.