The main objective of this study is to examine the incidence of back pain symptoms after caudal blockade (early and late

onset) GSK923295 in children.

Methods:

Patients under the age of 18 years, who received caudal blockade at the Montreal Children’s Hospital between July 2006 and December 2008 were recruited in this prospective observational study. Back pain was measured prospectively by patient self-report and parental observation during the 15-day postoperative period. Patients, or their parents, were contacted by phone on postoperative day 2 (POD2) and postoperative day 15 (POD15) to answer a seven-item symptom questionnaire.

Results:

In a sample of 135 children, the incidence of back pain symptoms was 4.7% and 1.1% on POD2 and POD15, respectively.

Conclusions:

The results of this study provide support Screening Library manufacturer that transient self-limiting back pain after caudal blockade does occur in pediatric patients. Clinically, this is useful information

for physicians to provide to their patients. An exploration of factors that may be associated with back pain following caudal blockade in children is an interesting area of future research.”
“Objective To compare the incidence of pain relief following injection of local anesthetic (LA) into lumbar discs that caused concordant pain during provocation testing. Design Prospective collected data review from two centers and compare with published results. Outcome Measures We compared subjective reported pain relief following provocative testing using the following protocols at three separate facilities: 23 patients undergoing routine provocative discography using contrast alone

selleck chemicals llc (PD); 47 patients undergoing provocative discography performed using an equal combination of LA and contrast (CPD); 120 patients injected with LA following routine PD (ADPD); 33 patients undergoing stand-alone analgesic discography (SAAD); and 28 patients injected with LA through a catheter (FAD) placed during provocative discogaphy testing. Results Pressure-controlled PD showed a positive response rate of 34% per disc in patients with a clinical diagnosis of discogenic pain. None of the PD group without LA had pain relief and less than 10% of the CPD group reported pain relief. Forty percent of the SAAD group with positive pain reproduction reported =50% relief and 20% reporting =80% relief. Forty-six percent of the ADPD group reported =50% relief and 30% reporting =80% relief. The FAD group had a greater 80% patients reporting =50% pain relief although fewer 26% reporting more convincing =80% relief. Conclusions If the criterion standard to confirm painful annular tears is concordant pain provocation and 80% or greater pain relief following LA injected into lumbar discs, the SAAD, ADPD, and FAD protocols show statistically similar 20% to 30% prevelance.