Design-Retrospective case series.
Animals-Client-owned dogs (n = 7) and cats (5).
Procedures-A custom-made lift device was used to retract the abdominal wall for laparoscopic instrumentation. The lift device was used first in 3 dog cadavers to assess the risk of complications. Thereafter, the device was used for routine laparoscopic procedures in client-owned JNJ-26481585 purchase animals. Data collected from medical records included signalment, body weight, clinical signs, diagnosis, surgery type and duration, conversion from laparoscopic to open surgery, preoperative American Society of Anesthesiologists score, mean intraoperative respiratory
rate, mean and peak end-tidal partial pressure of CO, during the laparoscopic surgery, ventilation method, mean saturation of hemoglobin with 02, mean and systolic arterial pressures during the laparoscopic surgery, total anesthesia time, signs of pain immediately after recovery, duration of hospitalization, and postoperative complications.
Results-Lift laparoscopy was successfully performed in 10 of the 12 patients. No adverse effects were noted with the use of this technique. However, in 1 dog and 1 cat, conversion to laparotomy was necessary because of poor visualization.
Conclusions and Clinical Relevance-Results suggested that lift laparoscopy is feasible in dogs and cats and is an option that can be used in clinical practice, especially
if creation INCB018424 manufacturer of positive-pressure pneumoperitoneum is not desirable. (J Am Metabolism inhibitor Vet Med Assoc 2011;239:1574-1579)”
“Background : IgA nephropathy (IgAN) is the most common glomerulonephritis
worldwide, and the clinical course of IgAN shows marked variability. Many efforts have made to histologically predict the clinical outcome. There are two methods to classify IgAN. One is mainly based on the glomerular changes, such as the WHO and the Lee and Haas classification systems. The other is a morphologic semi-quantitative scoring system, which counts the changes of the glomerular, tubulointerstitial and vascular structures, respectively. The purpose of this study is to determine whether the WHO classification property reflects the various morphologic findings of IgAN. Methods: We analyzed 354 cases of IgAN by both the WHO classification system and the semiquantitative scoring system and evaluated the correlations of these two methods. Results : The severity of the glomerular lesions (glomerulosclerosis, capsular adhesion and mesangial matrix expansion) and the tubulointerstitial lesions (interstitial fibrosis, tubular atrophy and interstitial lymphocytic infiltration) are strongly correlated with the increase of the WHO classes of IgAN (Spearman’s rho [R] >= 0.5, p < 0.05). There is a weak correlation between crescent formation and the increase of the WHO classes (R=0.3, p < 0.05).